Pilot Translational and Clinical Studies Program
Thank you to all who submitted a proposal for consideration! The review process has started and notification of awards will be provided by the end of October 2020. If you missed the application deadline this year, please be sure to check back in the spring of 2021 for details about the next funding opportunity.
The integrated Translational Health Research Institute of Virginia (iTHRIV) Pilot Translational and Clinical Studies (PTC) Program provides seed grant funding for early phase projects to accelerate joint discovery and the application of translational medical research. A core component of the iTHRIV NIH-funded Clinical and Translation Sciences Award is “Using Data to Improve Health” with a goal of helping teams transition from early-stage seed grants and proof-of concept studies to externally-funded translational research and clinical application.
The iTHRIV PTC Program is particularly interested in funding projects related to data science and those that involve collaboration across the iTHRIV partner institutions Inova, the University of Virginia, Virginia Tech and Carilion Clinic.
2020 Request for Proposals Timeline:
June 29th, 2020: Release RFP
July 9th, 2020 at 3 pm EST: Zoom information session
August 31st, 2020 by 5 pm: Application Deadline
October 23rd, 2020: Anticipated award notification date
February 1, 2021: Anticipated project start date
Proposals must involve an interdisciplinary team, and inclusion of multiple PIs or co-PIs is encouraged.
Any faculty member at an iTHRIV partner institution who is eligible to serve as a PI on external grants and contracts at their institution may serve as the contact PI for an application.
All projects involving human subjects must provide proper regulatory approvals prior to initiation of the research, but not prior to the submission of the proposal.
Non-Exempt human subject research for multi-site projects will be required to follow the NIH rule for use of a single IRB.
Teams should submit a single PDF containing the following:
Application Coversheet (template provided)
5-page project description (see below for details)
NIH formatted budget and budget justification (use provided templates)
NIH-style biosketch for each key personnel
The 5-page project description should include the following:
Description of Team Science
Plan for Community Engagement
Plan for Follow on Funding and Subsequent Research Studies
Mitigation Plan for how research will continue in the event of an ongoing pandemic
Funding and Awards:
Single-institution teams may request up to $25,000 of direct costs only, and multi-institution teams may request up to $50,000 of direct costs. All awards require approval from the National Institutes of Health, and funds must be expended within a single year (anticipated funding dates are approximately Feb, 1, 2021- Jan 31, 2022).
Teams should provide an NIH formatted budget and budget justification at the time of application, if the proposal includes collaboration with an iTHRIV partner institution please include separate budget and budget justifications for each institution. Formal approval by the appropriate grants offices will be requested only for those projects selected for funding. No carry over will be permitted.
Evaluation Criteria and Proposal Review:
iTHRIV PTC applications will be evaluated by reviewers from all four institutions and the top proposals recommended for funding. Applications will be evaluated based on the following criteria:
Does the project involve an innovative approach to an important clinical problem?
Is the project supported by appropriate preliminary data supporting the feasibility of translation to the clinic?
Does the project employ a team science approach and include personnel with the required expertise?Priority will be given to multi-site collaborative projects.
Is the project likely to lead to follow-on funding and/or translation to clinic?
Frequently Asked Questions
1) What does community engagement mean?
Identifying and communicating with stakeholders and end-users of the research process.
2) Are indirects allowed to be included in the budget?
For UVA budgets-No.
For all other institution budgets-federally negotiated indirect rates will apply.
3) Are references considered part of the 5-page project description?
No, references are separate as are the budget, budget justification, and NIH biosketches.
4) Are PI’s or Co-I’s required to have effort on the grant?
No, PI effort is discouraged, with this limited funding iTHRIV anticipates the majority of the funding will be needed for supplies, support staff, statistical support, etc.
5) Do proposals require review prior to submission by the grants and contracts office?
For UVA budgets (even if it is considered a sub-award)-No.
For all other institutions-recommend checking with the grants office and following local policies.
6) If this is a multi-institution project, are separate budgets and budget justifications required?
Yes-see question #2 for information regarding indirect rates.
7) If this is a multi-institution project, are the budgets required to be split evenly between institutions?
No-the budgets should be comparable to the work being done at each site.
Additional questions regarding subcontracts or sub-awards? Please contact Kayla Calvo KRC7D@hscmail.mcc.virginia.edu
Links for the Forms and July 9th Information Session Slides:
Questions? Need help finding a partner for a project?
June 29th, 2020:
August 31st, 2020
5 pm EST
February 1, 2021:
Anticipated project start
July 9th, 2020
3 pm EST:
Zoom information session
October 23rd, 2020:
Anticipated award notification date