OVERVIEW:

The iTHRIV Clinical and Translational Science (CTS) Pilot Studies Program is a core component of the NIH-funded Clinical and Translational Sciences Award (CTSA).  iTHRIV is a statewide collaborative research network with a mission of using data to improve health. 

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The iTHRIV CTS Pilot Studies Program seeks to develop innovative approaches to translational science (TS) projects, and foster collaboration across iTHRIV institutions. TS seeks to understand the scientific and operational principles underlying the translational research process. TS is focused on the general case that applies to any target or disease (see examples of TS projects below). Translational research (TR) projects solely focused on a particular target or disease are not allowed. Please see this learning short video.

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The CTS Program is intended to (1) explore possible innovative new leads or new directions for established investigators; (2) stimulate investigators from other areas to lend their expertise in research to CTS; and (3) provide initial support to establish proof of concept. 

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Examples of TS projects may include, but are not limited to:

• Development of new research methodology and/or new technologies/tools/resources that will advance CTS and thus increase the efficiency and effectiveness of translation.

• Early-stage development of new therapy/technology with generalizable application to an identified translational roadblock.

• Demonstrate in a particular use case(s) that the new methodology or technology advances translational science by successfully making one or more steps of the translational process more effective or efficient.

• Dissemination of effective tools, methods, processes, and training paradigms.

• Feasibility/proof of concept studies to support future CTS projects.

• Development of educational or training modules advancing the science of translation.

• Development of tools/technology/strategies to overcome barriers to research including barriers to study enrollment.​