iTHRIV Scholars Two Year Program

Core Curriculum

In addition to learning from conducting their proposed mentored iTHRIV research project, Scholars come together one afternoon a week to engage together in a core curriculum designed to prepare them for a future in clinical and/or translational health research.  Our curriculum draws from the core competencies identified for clinical and translational research as well as the fundamental characteristics of a translational scientist with added emphasis on principles and practices of data science, the art and skill of writing good grants, scientific integrity and responsible research, peer mentoring, and professional development.  The following chart depicts key threads along with examples of specific sessions from previous years where we have taken a “deeper dive” into those threads.  The iTHRIV Scholars Program continues to diversify, and each year the Scholars receive a uniquely tailored version of the core curriculum.  The delivery of this curriculum is heavily dependent on Scholar feedback as well as on the gaps and trajectories of each specific cohort of Scholars, and it is primarily delivered through a flipped classroom approach.  The newly integrated Scholars Program includes Scholars from UVA and VTC and features instructors from UVA, Virginia Tech, Carilion Clinic, Center for Open Science, UVA Licensing and Ventures Group, and elsewhere. Currently we are using Zoom to gather together for our core sessions.

While we provide a wide variety of focused material through the core curriculum, Scholars elect to supplement this training with additional certificate programs or Master’s degrees as determined by their own professional development needs (for example, prior Scholars have pursued formal training programs in Data Science, Clinical Research, Regulatory Science and Implementation Science).  Our curriculum team is always available to discuss these opportunities as well as the more specific details of the training we provide so that Scholars can make the most appropriate and efficient decisions for their career development plans.

DATA SCIENCE:

Introduction to Data Science

Introduction to TriNetX

Introduction to Clinical Informatics

Principles of Data Visualization and Tableau

Data Visualization Workshop

Hackathon

Clean Data from Compliance to Computation:  Data Provenance and Version Control in Excel

Data Science/Computational T Course

  • Introduction to R

  • Data Manipulation/Management/Cleaning

  • Advanced Data Visualization with R and ggplot2

  • Data Science Refresher

  • Reproducible Research and Dynamic Documents/Essential Statistics

  • Survival Analysis and Predictive Modeling

  • Intro to RNA-seq Data Analysis

  • Bring Your Own Data (series)

Data Integration and data integration repositories

History of data science and the development of the core domains of data science

TEAM SCIENCE:

Introduction to the iTHRIV portal

Thriving in an Era of Team Science – Case Discussion

“Convergence and Team Science” as part of the Science of Team Science Virtual Conference

COMMUNITY/POLICY:

Community-Based Participatory Research

Health Policy Research and Practice

The Equity Coalition (Health Disparities Work in Progress)

Overview of THRIV/iTHRIV Community Engagement Efforts

 “Equitable collaboration”:  Promoting just processes to grow resilient communities, durable outcomes and accountable public spaces, as we help communities learn where they’ve been, meet them where they are, and shape where they need/want to go

INNOVATION and COMMERCIALIZATION:

Principles and Practices of Licensing and Commercialization (series)

Commercialization and small business development for researchers and SBIR/STTR

RIGOR/TRANSPARENCY/REPRODUCIBILITY:

Introduction to Open Science Philosophy and Practices

Overview and Workshop– Center for Open Science

Health Sciences Library Resource Overview

Introduction to Pre-Prints:  the Good, the Bad, and the Ugly

Panel Discussion:  Data Security, Compliance, Reproducibility, and Resources (COS, UVA, UVAHS, UVA HSL)

SCIENTIFIC INTEGRITY/RESEARCH ETHICS/STUDY DESIGN CHALLENGES:

Big Data and Ethics

Clinical Translational Research Ethics – Scouting the Territory and Mapping the Landscape

Clinical Translational Research Ethics (Gelsinger Case)

Ethics in 15 Minutes (series), Translating E-15 to Your Workplace

Study Design Challenges

  • Overview of Study Design

  • Adaptive Study Design

  • Study Design Challenge (Surgical Trials with Sham Surgery Arms with Cognitively Impaired Participants)

  • Implicit Bias and Study Design

Biostatistics Refreshers (series)

FDA Therapeutics and the Need for Real World Evidence

Principles and Practices to Ensure Ethical Human Subjects Research

  • Introduction to the IRB

  • IRB Meeting (attend)

  • IRB Meeting Debrief

  • Mock IRB Session

Responsible Conduct of Research (RCR) Course

  • Intro to RCR and Research Misconduct

  • Authorship, Publication, and Peer Review

  • Data Management, Rigor, and Reproducibility

  • Collaborative Research and Conflicts of Interest

  • Research Integrity and Mentor/Trainee Responsibilities and Relationships

  • Research Involving Vertebrate Animals or Human Subjects

Introduction to DSMBs and OSMBs

Conflict of Interest

Research Continuity/Impact of COVID-19 on Research

GRANTS:

K and R Award Grant Writing and Preparation (series)

THRIV Grant Self Review (Career Development Mock Study Section)

K and R Mock Study Sections

VPR Office Proposal Development

NIH Proposal Development Webinar Series (6 plus materials)

Funding Sources:  Foundations, DOD, NSF, etc.

Building Your Budget

PERSONAL AND PROFESSIONAL DEVELOPMENT AND LEADERSHIP SKILLS:

Developmental Networks and Mentoring

Coaching – Getting Stuff Done and Enhancing Productivity

Your Brain at Work

Strength Finders

Writing Accountability Group (series)

Open House with THRIV PIs (monthly)

Individualized Learning Plans/Goal Setting –Implementing, Refining, and Holding Oneself Accountable

Cross-Grounds Resource Treasure Hunt

Building Your Translational Research Network (Interview Reports)

CV Review for Promotion and Tenure and Beyond

Resilience (series)

Immunity to Change

Peer mentoring – giving and receiving feedback

  • Presenting your research to your peers

  • Providing feedback to your peers

  • Bring Your Own Work in Progress (regular series)

Working from Home – Perspectives from Across the Continuum of Translational and Home-Life Environments

COMMUNICATION SKILLS (INTERPERSONAL AND TO AUDIENCES):

Ask Me About My Research - Communication Strategies (series)

Healthy Dialogues

THRIV Symposium Presentations (annual)

Editor’s Corner

Media Readiness Training

Pitch Decks – Dry Run Presentations at LVG

Pitch Decks - Formal Presentations at July Kickoff Session

MENTORING LUNCHEONS and MENTORING HOUR:

Cultivating Integrity in Your Research Team

Independence in an Era of Team Science

Imparting Grantsmanship Lessons Learned

Education about NIH Peer Review – Helpful and Potentially Missing Resources

Work/Life Balance

Team Science

Community-Based Participatory Research

Concepts of Big Data and Ethics

Health Policy Research and Practice

Value of Effective Mentoring Relationships

Lessons Learned (Work/Life Balance and Managing Multiple Priorities)

You must choose, and choose wisely:  Asking for, agreeing to, and declining collaboration

Mitigating the impact of the pandemic on early career clinical translational researchers and general discussion

Wet, Damp, and Dry:  negotiating for space with your mentor/mentee in university research settings

What it means to engage in team science, and how a recent shift to this model has implications for mentoring relationships

What do we actually do when we “mentor” or advise, sponsor, coach, etc.?

Introduction of the International Max Plank Research School on the Life Course (LIFE) and other interdisciplinary activities at the UVA College of Arts and Sciences

What role does “race” play in your field or in the research your team conducts?  Should mentors/mentees have explicit discussions about this?

Mentoring Skills – a review of the University of Wisconsin Mentoring Program

What translational science is and what a translational scientist is) and how we can mentor one another to lead translational science into the future

Being a Mentor and Ally:  A Community Discussion

What is “translational science” and “translational research”?  What does it mean to be a “translational scientist/researcher”?  Mentoring the next generation on their journey to becoming translational scientists

Perseverance through the resubmission process:  how effective mentoring can make the difference

Benefit or Burden: LGBTQ+ Inclusion in Research: an exploration of intentionality and its potential payoff

integrated Translational Health Research Institute of Virginia - 434-924-6208 - iTHRIVAdmin@hscmail.mcc.virginia.edu

iTHRIV is funded by the National Center for Advancing Translational Science of the National Institutes of Health Awards UL1TR003015/ KL2TR003016.  Contents of this website do not necessarily reflect the views of the institution and/or the National Institutes of Health.